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Comprehensive Analysis of Juvenile Nasopharyngeal Angiofibromas via Whole‐Exome Sequencing

The molecular basis and mechanisms of juvenile nasopharyngeal angiofibromas (JNA) pathogenesis are still unknown. Despite being a rare and benign neoplasm, JNA is a locally aggressive and potentially destructive head… Click to show full abstract

The molecular basis and mechanisms of juvenile nasopharyngeal angiofibromas (JNA) pathogenesis are still unknown. Despite being a rare and benign neoplasm, JNA is a locally aggressive and potentially destructive head and neck neoplasm, typically found in young males. The advancement of genome technologies and analytical tools has provided an unparalleled opportunity to explore the intricacy of JNA. The present study provides the first evidence of the involvement of Y‐chromosome genes in JNA.

Keywords: nasopharyngeal angiofibromas; angiofibromas via; juvenile nasopharyngeal; analysis juvenile; comprehensive analysis

Journal Title: Genes
Year Published: 2024

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