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Late‐onset major depression is associated with age‐related white matter lesions in the brainstem

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Age‐related white matter lesions (ARWMLs) have been identified in various clinical conditions such as reduced gait speed, cognitive impairment, urogenital dysfunction, and mood disturbances. Previous studies indicated an association between… Click to show full abstract

Age‐related white matter lesions (ARWMLs) have been identified in various clinical conditions such as reduced gait speed, cognitive impairment, urogenital dysfunction, and mood disturbances. Previous studies indicated an association between ARWML and late‐onset major depression. However, most of these focused on the extent of supratentorial ARWML and neglected presence and degree of infratentorial lesions.

Keywords: late onset; matter lesions; onset major; age related; related white; white matter

Journal Title: International Journal of Geriatric Psychiatry
Year Published: 2017

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