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Mitochondrial DNA (mtDNA) heteroplasmy is a mixture of normal and mutated mtDNA molecules in a cell. High levels of heteroplasmy at several mtDNA sites in complex I lead to inherited… Click to show full abstract
Mitochondrial DNA (mtDNA) heteroplasmy is a mixture of normal and mutated mtDNA molecules in a cell. High levels of heteroplasmy at several mtDNA sites in complex I lead to inherited neurological neurologic diseases and brain magnetic resonance imaging (MRI) abnormalities. Here, we test the hypothesis that mtDNA heteroplasmy at these complex I sites is associated with depressive symptoms in the elderly.
Keywords:
associated depressive;
depressive symptoms;
symptoms elderly;
heteroplasmy;
mitochondrial dna
Journal Title: International Journal of Geriatric Psychiatry
Year Published: 2018
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Journal Title: International Journal of Geriatric Psychiatry
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!