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The recency ratio is related to CSF amyloid beta 1‐42 levels in MCI‐AD

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As anti‐amyloid therapeutic interventions shift from enrolling patients with Alzheimer's disease (AD) dementia to individuals with pre‐clinical disease, the need for sensitive measures that allow for non‐invasive, fast, disseminable, and… Click to show full abstract

As anti‐amyloid therapeutic interventions shift from enrolling patients with Alzheimer's disease (AD) dementia to individuals with pre‐clinical disease, the need for sensitive measures that allow for non‐invasive, fast, disseminable, and cost‐effective identification of preclinical status increases in importance. The recency ratio (Rr) is a memory measure that relies on analysis of serial position performance, which has been found to predict cognitive decline and conversion to early mild cognitive impairment (MCI). The aim of this study was to test Rr's sensitivity to cerebrospinal fluid (CSF) levels of the core AD biomarkers in individuals with MCI‐AD and controls.

Keywords: ratio related; recency; recency ratio; related csf

Journal Title: International Journal of Geriatric Psychiatry
Year Published: 2019

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