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Tolerability of lithium: A naturalistic discontinuation study in older inpatients (≥60 years)

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Lithium is one of the most effective treatment options in both bipolar disorder and treatment‐resistant depression. The use of lithium in older patients declined during the last decades, probably resulting… Click to show full abstract

Lithium is one of the most effective treatment options in both bipolar disorder and treatment‐resistant depression. The use of lithium in older patients declined during the last decades, probably resulting in undertreatment of older patients. To investigate how well lithium is tolerated in old age, we aimed to determine the frequency, reasons, and possible predictors of discontinuation due to adverse effects in a cohort of inpatients ≥60 years who had started with lithium.

Keywords: naturalistic discontinuation; lithium naturalistic; lithium; inpatients years; tolerability lithium

Journal Title: International Journal of Geriatric Psychiatry
Year Published: 2021

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