LAUSR.org creates dashboard-style pages of related content for over 1.5 million academic articles. Sign Up to like articles & get recommendations!

Incidence of dementia in a population cohort of older people from São Paulo, Brazil Incidence of dementia in São Paulo, Brazil.

Photo from wikipedia

OBJECTIVE To estimate the incidence of dementia in a community-dwelling older population from São Paulo city, Brazil. METHODS /Design This two-phase prospective cohort study evaluated a representative cluster sample of… Click to show full abstract

OBJECTIVE To estimate the incidence of dementia in a community-dwelling older population from São Paulo city, Brazil. METHODS /Design This two-phase prospective cohort study evaluated a representative cluster sample of 1,370 individuals aged 60 years old and over from three different socioeconomic levels. The community screening phase consisted of a tested combination of cognitive and functional tests administered among the subjects and informants. In the hospital diagnosis phase, the Cambridge Examination was performed; the diagnosis of dementia and dementia subtypes was made according to DSM IV criteria. Incidence rates were expressed in person-years, multiplied by 1,000. The risk of developing dementia was calculated using Cox regression. RESULTS Among 1,370 eligible subjects, 678 were accessed, and 489 completed the evaluation. Forty-two subjects were diagnosed with dementia. The incidence rate of dementia and Alzheimer's disease (AD) were 11.2 (95% CI: 8.0 - 15.1) and 8.9 (95% CI: 6.1 - 12.5) per 1,000 person-years, respectively; there were high age-specific rates of dementia among younger individuals. There was a trend of a higher risk of developing AD for women than for men. Multivariate analysis showed that older age, the presence of diabetes and the presence of amnestic MCI increased the risk of developing dementia. Conclusions The age-specific rates in younger individuals were expressively higher than in worldwide studies and supposedly affected by cardiovascular morbidity. The higher risk in women in a younger sample corroborated the interaction between sex and AD. The increased risk of amnestic MCI reinforced its contribution to the progression to dementia and AD. This article is protected by copyright. All rights reserved.

Keywords: incidence; risk; brazil incidence; dementia; incidence dementia; paulo brazil

Journal Title: International journal of geriatric psychiatry
Year Published: 2021

Link to full text (if available)


Share on Social Media:                               Sign Up to like & get
recommendations!

Related content

More Information              News              Social Media              Video              Recommended



                Click one of the above tabs to view related content.