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Plasma 5‐HIAA activity indicative of serotonergic disturbances in cognitively impaired, elderly patients experiencing postoperative delirium

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Delirium frequently arises in older demented and non‐demented patients in postoperative, clinical settings. To date, the underlying pathophysiological mechanisms remain poorly understood. Monoamine neurotransmitter alterations have been linked to delirium… Click to show full abstract

Delirium frequently arises in older demented and non‐demented patients in postoperative, clinical settings. To date, the underlying pathophysiological mechanisms remain poorly understood. Monoamine neurotransmitter alterations have been linked to delirium and cognitive impairment. Our aim was to investigate if this holds true in cognitively normal and impaired patients experiencing delirium following hip surgery.

Keywords: plasma hiaa; patients experiencing; indicative serotonergic; delirium; hiaa activity; activity indicative

Journal Title: International Journal of Geriatric Psychiatry
Year Published: 2021

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