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Preserving LXR by inhibiting T39: A step closer to treating atherosclerosis and steatohepatitis?

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zumab, Secukinumab, and Brodalumab) are being evaluated for treatments of psoriasis, psoriatic arthritis, rheumatoid arthritis, and ankylosing spondylitis. The current study by Gomes and coworkers adds interesting insights into the… Click to show full abstract

zumab, Secukinumab, and Brodalumab) are being evaluated for treatments of psoriasis, psoriatic arthritis, rheumatoid arthritis, and ankylosing spondylitis. The current study by Gomes and coworkers adds interesting insights into the cellular and molecular mechanisms underlying IL-17-driven NAFLD progression, giving rise to the hope that the findings can be translated into novel therapeutics for NAFLD in the future.

Keywords: t39 step; closer treating; lxr inhibiting; inhibiting t39; preserving lxr; step closer

Journal Title: Hepatology
Year Published: 2017

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