Moderate-to-vigorous exercise increases blood ammonia concentrations, potentially contributing to the development of hepatic encephalopathy (HE). Patients with end-stage liver disease (ESLD) often suffer from frailty or physical deconditioning as a… Click to show full abstract
Moderate-to-vigorous exercise increases blood ammonia concentrations, potentially contributing to the development of hepatic encephalopathy (HE). Patients with end-stage liver disease (ESLD) often suffer from frailty or physical deconditioning as a result of sarcopenia, fluid overload/ascites, obesity and concomitant diseases. Exercise is therefore recommended for ESLD patients to reverse or halt progression of frailty/sarcopenia, as these conditions contribute to increased mortality.
               
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