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Deletion of Protein Kinase D3 Promotes Liver Fibrosis in Mice

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Liver fibrosis (LF) is a central pathological process that occurs in most types of chronic liver diseases. Advanced LF causes cirrhosis, hepatocellular carcinoma, and liver failure. However, the exact molecular… Click to show full abstract

Liver fibrosis (LF) is a central pathological process that occurs in most types of chronic liver diseases. Advanced LF causes cirrhosis, hepatocellular carcinoma, and liver failure. However, the exact molecular mechanisms underlying the initiation and progression of LF remain largely unknown.

Keywords: kinase promotes; liver fibrosis; promotes liver; deletion protein; fibrosis mice; protein kinase

Journal Title: Hepatology
Year Published: 2020

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