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Letter to the Editor: Issues of Circular RNAs as MicroRNA Sponges

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I read the article by Wei et al.(1) focusing on oncogenic functions and probable tumorigenesis-promoting mechanisms of circular chromodomain Y like (circ-CDYL)-microRNA-messenger RNA (mRNA)s axis as well as applications of… Click to show full abstract

I read the article by Wei et al.(1) focusing on oncogenic functions and probable tumorigenesis-promoting mechanisms of circular chromodomain Y like (circ-CDYL)-microRNA-messenger RNA (mRNA)s axis as well as applications of circ-CDYL as a noninvasive biomarker in the early stages of hepatocellular carcinoma diagnosis. Although circ-CDYL will play an important role and have a promising clinical application value, there is a misunderstanding regarding a biological function of most circular RNAs as microRNAs sponges in this manuscript.

Keywords: letter editor; circular rnas; rnas microrna; editor issues; circ cdyl; issues circular

Journal Title: Hepatology
Year Published: 2020

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