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Alcohol, Fasting, and Therapeutic Dosing of Acetaminophen: A Perfect Storm

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Acetaminophen (paracetamol, APAP) remains an ongoing public health problem more than 50 years after its introduction in the United Kingdom (UK) in the 1960's. Despite the presence of a highly… Click to show full abstract

Acetaminophen (paracetamol, APAP) remains an ongoing public health problem more than 50 years after its introduction in the United Kingdom (UK) in the 1960's. Despite the presence of a highly effective antidote, N-acetylcysteine, APAP toxicity continues to dwarf all other forms of drug-induced liver injury leading to acute liver failure in the Western world (1).

Keywords: acetaminophen perfect; therapeutic dosing; acetaminophen; dosing acetaminophen; fasting therapeutic; alcohol fasting

Journal Title: Hepatology
Year Published: 2021

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