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Exosomes and MicroRNA‐223 at the Intersection of Inflammation and Fibrosis in NAFLD

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Nonalcoholic fatty liver and nonalcoholic steatohepatitis (NASH) are the most common causes of liver disease. Progression of nonalcoholic fatty liver disease (NAFLD) to NASH is mediated by multiple signals that… Click to show full abstract

Nonalcoholic fatty liver and nonalcoholic steatohepatitis (NASH) are the most common causes of liver disease. Progression of nonalcoholic fatty liver disease (NAFLD) to NASH is mediated by multiple signals that include activation of inflammatory cells, such as neutrophil leukocytes, monocytes, and macrophages, in the liver and fibrotic processes due to stellate cell and myelofibroblast activation.(1).

Keywords: inflammation fibrosis; intersection inflammation; exosomes microrna; fibrosis nafld; microrna 223; 223 intersection

Journal Title: Hepatology
Year Published: 2021

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