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We read with enormous interest the study by Kamal et al.1 For the past two decades, dispute on the carcinogenic effects of PPI has remained. In this retrospective study using… Click to show full abstract
We read with enormous interest the study by Kamal et al.1 For the past two decades, dispute on the carcinogenic effects of PPI has remained. In this retrospective study using nationwide registries, long-term use of PPIs was identified to be associated with increased risks of gallbladder, intrahepatic and extrahepatic bile duct cancers. This study is the first large-scale population-based study assessing biliary tract cancer risks under PPI use, using high-quality data and well-designed methods. Despite the strengths of this study, several issues need further discussion.
Journal Title: Hepatology
Year Published: 2021
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