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Genome-wide association study of liver-related enzymes suggests putative pleiotropic effects on diverse traits and diseases.

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Over the last decade, genome-wide association studies (GWAS) have allowed for the dissection of the genetic susceptibility to complex liver diseases.1 In a recent issue of Nature communications, Chen and… Click to show full abstract

Over the last decade, genome-wide association studies (GWAS) have allowed for the dissection of the genetic susceptibility to complex liver diseases.1 In a recent issue of Nature communications, Chen and colleagues conducted a meta-analysis of GWAS collected in ~390,000 individuals of the UK BioBank and ~160,000 Japanese individuals from the BioBank Japan to expand the understanding of the genetic determinants of serum levels of liver-related enzymes.2.

Keywords: liver related; genome wide; related enzymes; association study; wide association

Journal Title: Hepatology
Year Published: 2021

Link to full text (if available)


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