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HCV‐specific T cells are few and exhausted in patients with chronic hepatitis C (CHC). Whether these T cells are responsible for the liver damage and fibrosis is still debated. However,… Click to show full abstract
HCV‐specific T cells are few and exhausted in patients with chronic hepatitis C (CHC). Whether these T cells are responsible for the liver damage and fibrosis is still debated. However, cluster of differentiation 38–positive (CD38+) human leukocyte antigen DR–positive (HLA‐DR+) CD8+ T cells are regarded as bystander CD8+ T cells that cause liver injury in acute hepatitis. We propose that these innate CD8+ T cells play a pathogenic role in CHC.
Keywords:
patients chronic;
chronic hepatitis;
cd8 cells;
hla cd8;
cd8
Journal Title: Hepatology
Year Published: 2022
Link to full text (if available)
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Journal Title: Hepatology
Year Published: 2022
Link to full text (if available)
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recommendations!