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Adult onset hemophagocytic lymphohistiocytosis prognosis is affected by underlying disease and coexisting viral infection: analysis of a single institution series of 35 patients

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Adult onset hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome, which can develop as a complication of many disorders. Early diagnosis is essential in order to avoid a fatal outcome. To… Click to show full abstract

Adult onset hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome, which can develop as a complication of many disorders. Early diagnosis is essential in order to avoid a fatal outcome. To confirm the diagnosis of acquired HLH made in a single institution series of adult patients with HLH‐04 criteria, we applied the HScore and evaluated prognostic factors associated with clinical outcome.

Keywords: onset hemophagocytic; adult onset; institution series; hemophagocytic lymphohistiocytosis; single institution

Journal Title: Hematological Oncology
Year Published: 2017

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