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CLL/SLL pts. Most surprisingly is the high rate of infusion related reactions; however, these were mainly confined to grade 2 reactions and grade 3 reactions were much lower than in… Click to show full abstract
CLL/SLL pts. Most surprisingly is the high rate of infusion related reactions; however, these were mainly confined to grade 2 reactions and grade 3 reactions were much lower than in the CLL11 trial (Goede V, NEJM 2014). While PFS is shorter compared to CLL11, this reflects both pts not completing therapy, as well as including pts in the r/r setting. Regardless, OBI remains an effective and well tolerated agent in both frontline and r/r pts with CLL/SLL who may not be eligible for other therapies.
Keywords:
therapy;
anti cd20;
cd20 frontline;
combination anti;
chlorambucil combination;
role chlorambucil
Journal Title: Hematological Oncology
Year Published: 2019
Link to full text (if available)
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Journal Title: Hematological Oncology
Year Published: 2019
Link to full text (if available)
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recommendations!