LAUSR

Multimodal medical image fusion merges two medical images to produce a visual enhanced fused image, to provide more accurate comprehensive pathological information to doctors for better diagnosis and treatment. In this article, we present a perceptual multimodal medical image fusion method with free energy (FE) motivated adaptive pulse coupled neural network (PCNN) by employing Internal Generative Mechanism (IGM). First, source images are divided into predicted layers and detail layers with Bayesian prediction model. Then to retain human visual system inspired features, FE is used to motivate the PCNN for processing detail layers, and large firing times are selected as coefficients. The predicted layers are fused with the averaging strategy as activity level measurement. Finally, the fused image is reconstructed by merging coefficients in both fused layers. Experimental results visually and quantitatively show that the proposed fusion strategy is superior to the state‐of‐the‐art methods.