LAUSR.org creates dashboard-style pages of related content for over 1.5 million academic articles. Sign Up to like articles & get recommendations!

Identification of white blood cells for the diagnosis of acute myeloid leukemia

Photo from wikipedia

The diagnosis of hematologic malignancies such as leukemia includes identifying malignant white blood cells. Manual microscopic analysis of white blood cells is time‐consuming and involves the assistance of medical specialists,… Click to show full abstract

The diagnosis of hematologic malignancies such as leukemia includes identifying malignant white blood cells. Manual microscopic analysis of white blood cells is time‐consuming and involves the assistance of medical specialists, and its accuracy may be affected by their abilities. Our objective is to develop an automated system that can identify 15 categories of white blood cells to assist medical practitioners in diagnosing acute myeloid leukemia. The proposed approach uses an ensemble model built with transfer learning‐based pre‐trained networks to categorize 15 kinds of white blood cells. An over‐sampling strategy is used to alleviate the problem of class imbalance, followed by data augmentation. For experimentation, a microscopic blood image dataset containing 18 365 cells images from 200 individuals representing 15 different forms of leukocytes is used. For cells with more than 400 images available, the suggested technique achieves an F1 score of more than 91%. Myeloblasts, which are frequent in myeloid leukemias and are detected in the peripheral blood, are recognized with an average precision of 95.74%. This work describes an image processing strategy that employs ensemble learning to assist in diagnosing acute myeloid leukemia by classifying 15 different types of leukocytes. Experiments show that our technique is both practical and effective. Extensive research supports the use of the leukocyte classifier in real‐world medical applications, such as assisting clinicians in diagnosing diseases and decreasing human resource requirements.

Keywords: myeloid leukemia; blood cells; acute myeloid; blood; white blood

Journal Title: International Journal of Imaging Systems and Technology
Year Published: 2022

Link to full text (if available)


Share on Social Media:                               Sign Up to like & get
recommendations!

Related content

More Information              News              Social Media              Video              Recommended



                Click one of the above tabs to view related content.