LAUSR

Lead by the original idea to perform noninvasive optical biopsies of various tissue, optical coherence tomography found numerous medical applications within the last two decades. The interference based imaging technique opens the possibility to visualise subcellular morphology up to an imaging depth of 3 mm and up to micron level axial and lateral resolution. The birefringence properties of the tissue are visualised with enhanced contrast using polarisation sensitive or cross polarised optical coherence tomography techniques. Although, it requires strict control over the polarisation states, resulting in several polarisation controlling elements. In this work, we propose a novel input-polarisaion independent endoscopic system based on cross polarised optical coherence tomography. We tested the feasibility of our approach by measuring the polarisation change from a quarter wave plate for different rotational angles. Further performance tests reveal a lateral resolution of 30 μm and a sensitivity of 103 dB. Images of the human nail-bed and cow muscle tissue demonstrate the potential of the system to measure structural and birefringence properties of the tissue endoscopically. This article is protected by copyright. All rights reserved.