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The Emperor's New Clothes: What Randomized Controlled Trials Don't Cover

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Randomized controlled trials are the bedrock of evidence-based medicine (EBM). They avoid the major pitfalls of anecdotal evidence, conscious and unconscious bias in patient selection and outcome assessments. Randomized clinical… Click to show full abstract

Randomized controlled trials are the bedrock of evidence-based medicine (EBM). They avoid the major pitfalls of anecdotal evidence, conscious and unconscious bias in patient selection and outcome assessments. Randomized clinical trials (RCTs) have revolutionized our knowledge of the efficacy and safety of medicines across all aspects of health care. They are now even being applied to surgical interventions.

Keywords: clothes randomized; randomized controlled; emperor new; new clothes; controlled trials; trials cover

Journal Title: Journal of Bone and Mineral Research
Year Published: 2018

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