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Hereditary thrombotic thrombocytopenic purpura, also called Upshaw‐Schulman syndrome (USS), is a rare disease caused by genetic mutations in the ADAMTS13 gene, which severely decrease the activity of ADAMTS13, a metalloprotease… Click to show full abstract
Hereditary thrombotic thrombocytopenic purpura, also called Upshaw‐Schulman syndrome (USS), is a rare disease caused by genetic mutations in the ADAMTS13 gene, which severely decrease the activity of ADAMTS13, a metalloprotease that cleaves von Willebrand factor multimers (VWF). Genotypically identical patients can show great phenotypic diversity.
Keywords:
adamts13 kinetics;
kinetics therapeutic;
upshaw schulman;
therapeutic plasma;
schulman syndrome
Journal Title: Journal of Clinical Apheresis
Year Published: 2019
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Journal Title: Journal of Clinical Apheresis
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!