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Tissue plasminogen activator vs heparin for locking central venous catheters between apheresis procedures

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Central venous catheters (CVCs) for apheresis procedures require regular locking/flushes to maintain adequate flow rates. Literature comparing locking solutions for apheresis, where the time interval between procedures can be longer… Click to show full abstract

Central venous catheters (CVCs) for apheresis procedures require regular locking/flushes to maintain adequate flow rates. Literature comparing locking solutions for apheresis, where the time interval between procedures can be longer than for hemodialysis (many days to weeks), is lacking. In this study, catheter malfunction rates using recombinant tissue plasminogen activator (rt‐PA) vs heparin for locking CVC between apheresis procedures were compared.

Keywords: apheresis procedures; venous catheters; central venous; apheresis; plasminogen activator; tissue plasminogen

Journal Title: Journal of Clinical Apheresis
Year Published: 2019

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