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Therapeutic plasma exchange in acute liver failure

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Multi‐organ dysfunction in acute liver failure (ALF) has been attributed to a systemic inflammatory response directly triggered by the injured liver. High‐volume therapeutic plasma exchange (HV‐TPE) has been demonstrated in… Click to show full abstract

Multi‐organ dysfunction in acute liver failure (ALF) has been attributed to a systemic inflammatory response directly triggered by the injured liver. High‐volume therapeutic plasma exchange (HV‐TPE) has been demonstrated in a large randomized controlled trial to improve survival. Here, we investigated if a more cost‐/ resource effective low‐volume (LV) TPE strategy might have comparable beneficial effects.

Keywords: therapeutic plasma; liver failure; plasma exchange; acute liver

Journal Title: Journal of Clinical Apheresis
Year Published: 2019

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