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Successful use of nonantigen‐specific immunoadsorption with antihuman Ig‐columns in kidney graft antibody‐mediated rejection

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Nonantigen‐specific immunoadsorption (IA) has proven to be effective in acute antibody‐mediated rejection (aAMR). However, there is a lack of solid studies evaluating the safety and efficacy of IA with antihuman… Click to show full abstract

Nonantigen‐specific immunoadsorption (IA) has proven to be effective in acute antibody‐mediated rejection (aAMR). However, there is a lack of solid studies evaluating the safety and efficacy of IA with antihuman Ig‐columns in aAMR. For chronic‐active AMR (cAMR), no studies have evaluated the efficacy of nonantingen‐specific IA with antihuman Ig‐columns. The purpose of this study was to evaluate the role of nonantigen‐specific IA with antihuman Ig‐columns in the treatment of both aAMR and cAMR in kidney transplantation.

Keywords: specific immunoadsorption; antihuman columns; mediated rejection; antibody mediated; nonantigen specific

Journal Title: Journal of Clinical Apheresis
Year Published: 2020

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