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Mobilized and apheresis‐collected endothelial progenitor cells with plerixafor

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Endothelial progenitor cells (EPCs) are immature cells able to proliferate and contribute to endothelial repair, vascular homeostasis, neovascularization, and angiogenesis. It therefore seems likely that circulating EPCs have therapeutic potential… Click to show full abstract

Endothelial progenitor cells (EPCs) are immature cells able to proliferate and contribute to endothelial repair, vascular homeostasis, neovascularization, and angiogenesis. It therefore seems likely that circulating EPCs have therapeutic potential in ischemic and vascular diseases. In this study we evaluated the efficiency of EPC mobilization and collection by large volume leukapheresis in subjects with hematological diseases, treated with plerixafor in association with G‐CSF.

Keywords: endothelial progenitor; progenitor cells; apheresis collected; mobilized apheresis

Journal Title: Journal of Clinical Apheresis
Year Published: 2022

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