"Algorithm‐based selection of automated red blood cell exchange procedure goals reduces blood utilization in chronically transfused adults with sickle cell disease"

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Automated red cell exchange (RCE) is a common treatment for patients with sickle cell disease (SCD). Two key parameters are used to determine the volume of blood for RCE to… Click to show full abstract

Automated red cell exchange (RCE) is a common treatment for patients with sickle cell disease (SCD). Two key parameters are used to determine the volume of blood for RCE to reduce sickle hemoglobin (eg, HbS): fraction of cells remaining (FCR) and target hematocrit. We evaluated how the calculated FCR—using the manufacturer's algorithm—impacted blood utilization and incidence of acute care encounters.

Keywords: cell; cell disease; cell exchange; blood; sickle cell; automated red

Journal Title: Journal of Clinical Apheresis
Year Published: 2022

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