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Oxymatrine ameliorates diabetes‐induced aortic endothelial dysfunction via the regulation of eNOS and NOX4

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Oxymatrine (OMT) is the major quinolizidine alkaloid extracted from the root of Sophora flavescens Ait (the Chinese herb Kushen) and exhibits diverse pharmacological actions. In this study, we investigated the… Click to show full abstract

Oxymatrine (OMT) is the major quinolizidine alkaloid extracted from the root of Sophora flavescens Ait (the Chinese herb Kushen) and exhibits diverse pharmacological actions. In this study, we investigated the effects of OMT on diabetes‐associated aortic endothelial dysfunction in a rat model of diabetes and its mechanisms.

Keywords: ameliorates diabetes; oxymatrine ameliorates; diabetes induced; endothelial dysfunction; aortic endothelial

Journal Title: Journal of Cellular Biochemistry
Year Published: 2018

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