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Long noncoding RNA myocardial infarction–associated transcript regulated the pancreatic stellate cell activation to promote the fibrosis process of chronic pancreatitis

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Long noncoding RNAs (lncRNAs) play crucial roles in fibrosis process. In our previous RNA‐seq study, we found that lncRNA myocardial infarction–associated transcript (MIAT) was differentially expressed in pancreatic tissues of… Click to show full abstract

Long noncoding RNAs (lncRNAs) play crucial roles in fibrosis process. In our previous RNA‐seq study, we found that lncRNA myocardial infarction–associated transcript (MIAT) was differentially expressed in pancreatic tissues of chronic pancreatitis (CP) patients. However, the function of MIAT in CP remains unknown. This study was aimed to investigate the function and underlying mechanism of MIAT in pancreatic fibrosis.

Keywords: long noncoding; fibrosis; myocardial infarction; fibrosis process; associated transcript; infarction associated

Journal Title: Journal of Cellular Biochemistry
Year Published: 2019

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