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The Podocyte Count Detected by an Improved Immunocytochemical Method has Higher Diagnostic Efficiency than Enzyme‐Linked Immunosorbent Assay and Serum Cystatin C to Evaluate the Early Stage Damage of Glomerular

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In renal diseases, earlier injury to glomerular may lead to the abscission of podocyte. The number of podocyte in urine may reflect the severity of glomerular damage. Podocalyxin (PCX) was… Click to show full abstract

In renal diseases, earlier injury to glomerular may lead to the abscission of podocyte. The number of podocyte in urine may reflect the severity of glomerular damage. Podocalyxin (PCX) was considered as a podocyte marker. Many methods were used to detect podocyte. Applications of these methods were limited by tricky, expensive, and low accuracy. Here, we improved an immunocytochemical method to count the number of podocyte in urine.

Keywords: improved immunocytochemical; podocyte; damage; count; immunocytochemical method

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2017

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