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Platelet aggregometry cannot identify uremic platelet dysfunction in heart failure patients prior to cardiac surgery

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Patients with heart failure often have concomitant renal disease which can result in uremic platelet dysfunction. Determining whether uremia has affected platelets by platelet aggregometry can be challenging in these… Click to show full abstract

Patients with heart failure often have concomitant renal disease which can result in uremic platelet dysfunction. Determining whether uremia has affected platelets by platelet aggregometry can be challenging in these patients since they are often on antiplatelet medications. This study was undertaken to determine if platelet aggregation studies could identify heart failure patients at risk for uremic bleeding prior to cardiac surgery.

Keywords: platelet; uremic platelet; platelet dysfunction; heart failure

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2017

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