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Association of 758 G/A polymorphism of 3′untranslated region of prohibitin with risk of gastric cancer

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A polymorphic variant allele (T‐allele) in the 3′‐UTR of prohibitin (C‐to‐T at nucleotide 729) was reported to be associated with an increased risk of breast cancer. However, the association between… Click to show full abstract

A polymorphic variant allele (T‐allele) in the 3′‐UTR of prohibitin (C‐to‐T at nucleotide 729) was reported to be associated with an increased risk of breast cancer. However, the association between the 3′‐UTR polymorphism of prohibitin and the susceptibility to gastric cancer remains unknown. Thus, we investigated the distribution of prohibitin genotypes in Chinese patients with gastric cancer and subsequently analyzed the association between the 3′‐UTR polymorphism of prohibitin and the risk of gastric cancer in that population.

Keywords: risk; gastric cancer; association; cancer; prohibitin; polymorphism

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2018

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