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The clinical significance of DJ‐1 and HE4 in patients with endometrial cancer

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The non‐invasive diagnostic approach for early detection of endometrial cancer (EC) remains limited. To date, human epididymis protein 4 (HE4) has been intensively studied but its diagnostic is controversial in… Click to show full abstract

The non‐invasive diagnostic approach for early detection of endometrial cancer (EC) remains limited. To date, human epididymis protein 4 (HE4) has been intensively studied but its diagnostic is controversial in EC. DJ‐1 is an oncoprotein secreted by cancer cells, recently identified as a potential diagnostic biomarker for breast cancer, melanoma, and pancreatic cancer. The aim of this study was to compare the diagnostic performances of DJ‐1 and HE4 measured in EC patients and healthy controls (HC).

Keywords: he4 patients; patients endometrial; endometrial cancer; cancer; clinical significance; significance he4

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2018

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