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Identification of sequence polymorphisms in the mitochondrial cytochrome c oxidase genes as risk factors for hepatocellular carcinoma

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Single nucleotide polymorphisms (SNPs) accumulated in the mitochondrial DNA (mtDNA) is susceptible to the tumor formation. We discovered previously that SNPs in the mitochondrial displacement loop (D‐loop) was associated with… Click to show full abstract

Single nucleotide polymorphisms (SNPs) accumulated in the mitochondrial DNA (mtDNA) is susceptible to the tumor formation. We discovered previously that SNPs in the mitochondrial displacement loop (D‐loop) was associated with the risk of hepatocellular carcinoma (HCC).

Keywords: hepatocellular carcinoma; polymorphisms mitochondrial; risk; sequence polymorphisms; identification sequence

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2018

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