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Circulating cell‐free high mobility group AT‐hook 2 mRNA as a detection marker in the serum of colorectal cancer patients

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Detection of circulating cell‐free mRNA serves as noninvasive tools for cancer diagnosis. As an oncofetal protein, HMGA2 (high mobility group AT‐hook 2) is upregulated in colorectal cancer (CRC) tissues. However,… Click to show full abstract

Detection of circulating cell‐free mRNA serves as noninvasive tools for cancer diagnosis. As an oncofetal protein, HMGA2 (high mobility group AT‐hook 2) is upregulated in colorectal cancer (CRC) tissues. However, it is not clear whether the increased levels of circulating cell‐free HMGA2 mRNA functions as potential biomarkers for improved diagnosis of CRC.

Keywords: high mobility; cell free; circulating cell; cancer; mobility group

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2018

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