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The evaluation of two genetic polymorphisms of paraoxonase 1 in patients with pulmonary embolism

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Pulmonary embolism (PE) is caused by some genetic factors for more than half patients. Paraoxonase 1 (PON1) has significant anti‐oxidative and anti‐inflammatory effects. According to our knowledge, there is no… Click to show full abstract

Pulmonary embolism (PE) is caused by some genetic factors for more than half patients. Paraoxonase 1 (PON1) has significant anti‐oxidative and anti‐inflammatory effects. According to our knowledge, there is no study researching the relation between PON 1 gene polymorphisms and PE in the literature. Therefore, it is aimed to research possible impacts of PON 1 Q192R and L55M polymorphisms on PE, considering anti‐inflammatory and anti‐oxidative effects of PON 1 in Turkish population.

Keywords: evaluation two; pulmonary embolism; genetic polymorphisms; two genetic; embolism; polymorphisms paraoxonase

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2018

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