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High mobility group box 1 as a biomarker in critically ill patients

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Extracellular release of high mobility group box 1 (HMGB1) acts as a danger‐associated molecular pattern, thereby “alarming” the immune system and promoting systemic inflammation. We investigated plasma HMGB1 concentrations as… Click to show full abstract

Extracellular release of high mobility group box 1 (HMGB1) acts as a danger‐associated molecular pattern, thereby “alarming” the immune system and promoting systemic inflammation. We investigated plasma HMGB1 concentrations as a potential diagnostic and prognostic biomarker in critical illness.

Keywords: mobility group; group box; high mobility

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2018

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