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What makes D‐dimer assays suspicious–heterophilic antibodies?

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Heterophilic antibodies are still an important source of interference in immunoassays, but reports of interference with D‐dimers are rare. Are D‐dimer level abnormalities, found in the clinic, caused by heterophilic… Click to show full abstract

Heterophilic antibodies are still an important source of interference in immunoassays, but reports of interference with D‐dimers are rare. Are D‐dimer level abnormalities, found in the clinic, caused by heterophilic antibodies as well, or are other mechanisms involved? We will elaborate on this issue through two different examples in this article.

Keywords: assays suspicious; heterophilic antibodies; makes dimer; dimer assays; suspicious heterophilic

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2019

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