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Vitamin D levels and vitamin D receptor variants are associated with chronic heart failure in Chinese patients

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Vitamin D is an indispensable molecule for human health. Wide ranges of diseases are linked with vitamin D deficiencies. Role of vitamin D in chronic heart failure has been demonstrated… Click to show full abstract

Vitamin D is an indispensable molecule for human health. Wide ranges of diseases are linked with vitamin D deficiencies. Role of vitamin D in chronic heart failure has been demonstrated in different populations; however, reports are limited in Chinese population. Vitamin D exerts its effect through vitamin D receptor and variants in vitamin D receptor (VDR) gene are shown to affect vitamin D signaling. In the present study, we hypothesized that both vitamin D levels and VDR variants could be associated with the development of chronic heart failure.

Keywords: vitamin; chronic heart; vitamin receptor; heart failure

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2019

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