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A method for improving the efficiency of DNA extraction from clotted blood samples

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The efficient and rapid extraction of high‐quality genomic DNA from clotted blood samples, which normally have a low yield and poor quality, is an important factor in genomic research. The… Click to show full abstract

The efficient and rapid extraction of high‐quality genomic DNA from clotted blood samples, which normally have a low yield and poor quality, is an important factor in genomic research. The objective of this study was to develop a simple and safe technique for dispersing the blood clots by the ball bearing metal shots. Normally, such clot samples may not have an acceptable yield by conventional DNA extraction methods. Also, in the present study, we have further investigated to improve salting‐out DNA extraction methods.

Keywords: clotted blood; extraction; blood samples; dna extraction

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2019

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