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Comparison of performance characteristics between high‐performance liquid chromatography and latex agglutination turbidimetric immunoassay for therapeutic drug monitoring of zonisamide

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Recently, the Nanopia® TDM Zonisamide reagent using the latex particle‐enhanced turbidimetric immunoassay (LTIA) method was developed. The aim of this study was to compare the differences in serum zonisamide (ZNS)… Click to show full abstract

Recently, the Nanopia® TDM Zonisamide reagent using the latex particle‐enhanced turbidimetric immunoassay (LTIA) method was developed. The aim of this study was to compare the differences in serum zonisamide (ZNS) concentrations quantified by the high‐performance liquid chromatography (HPLC) method and the LTIA method using a TBA‐25FR analyzer.

Keywords: zonisamide; turbidimetric immunoassay; liquid chromatography; performance; high performance; performance liquid

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2019

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