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Association of polymorphisms in the HBG1‐HBD intergenic region with HbF levels

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Increased levels of fetal hemoglobin (HbF) can improve the clinical course of the patients with sickle cell anemia (SCA) or β‐thalassemia. The HBG1‐HBD intergenic region plays an important role in… Click to show full abstract

Increased levels of fetal hemoglobin (HbF) can improve the clinical course of the patients with sickle cell anemia (SCA) or β‐thalassemia. The HBG1‐HBD intergenic region plays an important role in this process. However, very few studies investigated whether the variations in this region have an effect on HbF expression.

Keywords: hbf; association polymorphisms; intergenic region; hbg1 hbd; hbd intergenic; region

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2020

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