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Wilms tumor is a frequently diagnosed renal cancer among children with unclear genetic causes. N6‐methyladenosine (m6A) modification genes play critical roles in tumorigenesis. However, whether genetic variations of m6A modification… Click to show full abstract
Wilms tumor is a frequently diagnosed renal cancer among children with unclear genetic causes. N6‐methyladenosine (m6A) modification genes play critical roles in tumorigenesis. However, whether genetic variations of m6A modification genes predispose to Wilms tumor remain unclear. ALKBH5 (AlkB homolog 5), a crucial member of m6A modification genes, encodes a demethylase that functions to reverse m6A RNA methylation.
Keywords:
m6a modification;
gene polymorphisms;
alkbh5 gene;
wilms tumor;
modification genes;
tumor
Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2020
Link to full text (if available)
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Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2020
Link to full text (if available)
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recommendations!