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Monocyte subsets to differentiate chronic myelomonocytic leukemia from reactive monocytosis

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Chronic myelomonocytic leukemia (CMML) is characterized by persistent monocytosis and dysplastic features of blood cells. No specific genetic abnormalities are present in CMML, and reactive monocytosis should be excluded. An… Click to show full abstract

Chronic myelomonocytic leukemia (CMML) is characterized by persistent monocytosis and dysplastic features of blood cells. No specific genetic abnormalities are present in CMML, and reactive monocytosis should be excluded. An increase in classical monocytes (MO1) has been suggested as a screening tool for CMML.

Keywords: monocytosis; monocyte subsets; chronic myelomonocytic; reactive monocytosis; myelomonocytic leukemia

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2020

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