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Signal transducer and activator of transcription family is a prognostic marker associated with immune infiltration in endometrial cancer

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Signal transducer and activator of transcription (STAT) is a unique protein family that binds to DNA and plays a vital role in regulating major physiological cellular processes. Seven STAT genes… Click to show full abstract

Signal transducer and activator of transcription (STAT) is a unique protein family that binds to DNA and plays a vital role in regulating major physiological cellular processes. Seven STAT genes have been identified in the human genome. Several studies suggest STAT family members to be involved in cancer development, progression, and metastasis. However, the predictive relationship between STAT family expression and immune cell infiltration in endometrial cancer remains unknown.

Keywords: family; signal transducer; infiltration endometrial; activator transcription; cancer; transducer activator

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2022

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