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MALT1 positively relates to Th17 cells, inflammation/activity degree, and its decrement along with treatment reflects TNF inhibitor response in ankylosing spondylitis patients

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Mucosa‐associated lymphoid tissue lymphoma translocation protein 1 (MALT1) facilitates CD4+ T‐cell differentiation, immune response, inflammation, and osteoclastogenesis. This study aimed to explore the relation between MALT1 and treatment efficacy to… Click to show full abstract

Mucosa‐associated lymphoid tissue lymphoma translocation protein 1 (MALT1) facilitates CD4+ T‐cell differentiation, immune response, inflammation, and osteoclastogenesis. This study aimed to explore the relation between MALT1 and treatment efficacy to tumor necrosis factor inhibitor (TNFi) in ankylosing spondylitis (AS) patients.

Keywords: inflammation; spondylitis patients; inhibitor; treatment; response; ankylosing spondylitis

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2022

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