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The genetic investigation of essential thrombocythemia(ET) has highlighted the presence of driver mutations in ET. Janus kinase JAK2V617F and calreticulin(CALR) mutations are the most frequent driver mutations and have significantly… Click to show full abstract
The genetic investigation of essential thrombocythemia(ET) has highlighted the presence of driver mutations in ET. Janus kinase JAK2V617F and calreticulin(CALR) mutations are the most frequent driver mutations and have significantly improved the molecular diagnosis of ET. The impact of genetic heterogeneity on clinical features has not been fully elucidated.
Keywords:
essential thrombocythemia;
calreticulin;
v617f calreticulin;
hematological relevance;
relevance jak2;
jak2 v617f
Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2022
Link to full text (if available)
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Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!