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Performance evaluation of a laboratory‐developed light‐initiated chemiluminescence assay for quantification of egg white‐specific IgE

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Specific IgE (sIgE) testing has become one of the most important tools for diagnosing IgE‐mediated food allergy. Enzyme‐linked immunosorbent assay (ELISA) and dot‐enzyme‐linked immunosorbent assay (Dot‐ELISA) have been used to… Click to show full abstract

Specific IgE (sIgE) testing has become one of the most important tools for diagnosing IgE‐mediated food allergy. Enzyme‐linked immunosorbent assay (ELISA) and dot‐enzyme‐linked immunosorbent assay (Dot‐ELISA) have been used to measure sIgE in clinical widely. Light‐initiated chemiluminescence assay (LICA) is a new method for measuring allergen‐sIgE. We aimed to establish a LICA method for quantitative detection of egg white‐sIgE and evaluate its performances.

Keywords: assay; specific ige; initiated chemiluminescence; ige; chemiluminescence assay; light initiated

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2022

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