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Increased level of free‐circulating MtDNA in maintenance hemodialysis patients: Possible role in systemic inflammation

Mitochondrial DNA (MtDNA) exposed to the extracellular space due to cell death and stress has immunostimulatory properties. However, the clinical significance of circulating MtDNA in maintenance hemodialysis (MHD) patients and… Click to show full abstract

Mitochondrial DNA (MtDNA) exposed to the extracellular space due to cell death and stress has immunostimulatory properties. However, the clinical significance of circulating MtDNA in maintenance hemodialysis (MHD) patients and the precise mechanism of its emergence have yet to be investigated.

Keywords: mtdna maintenance; increased level; maintenance hemodialysis; circulating mtdna

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2022

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